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All 55 samples that were malignant were classified as malignant on histopathological evaluation cytologically, and all were considered to be suspicious for malignancy according to the gene-expression classifier . A wide variety of malignant subtypes were correctly classified as suspicious for malignancy regarding to this test . These included papillary, medullary, and follicular thyroid carcinomas ; poorly differentiated thyroid carcinomas; and thyroid lymphomas. There were seven false negative results . To raised understand potential causes of false negative results, we measured single molecular markers described in the literature as being elevated in papillary thyroid carcinoma.