The institutional review board or independent ethics committee at each participating organization approved the process. The statistical program was reviewed by two independent academic statisticians. The known associates of the steering committee had been mixed up in study design, reviewed the protocol, and provided guidance on the study conduct. An independent safety and data monitoring plank reviewed all basic safety data in an unblinded fashion at regular intervals. All of the authors had usage of the info, contributed to data interpretation, contributed to composing the manuscript, approved and examined the final version, and made the decision to send the manuscript for publication.Overall, the results of the FWF project indicate that the consequences of extreme sport have become much dependent on the fitness of the individual up to the molecular level. Original publication: No acute and persistent DNA Harm after an Ironman Triathlon. S. Reichhold, O. Neubauer, V. Ehrlich, S.-H. Wagner, Cancers Epidemiol Biomarkers Prev 2008, 17, 1913-1919. Doi: 10.1158/1055-9965.EPI-08-0293.. A 65-year-old man with increasing difficulty walking A retired guy presents with features of spinal cord dysfunction, including a disturbed gait. What diagnoses is highly recommended and how should he be treated? Case presentation History and examination A retired 65-year-old guy presented to his general practitioner describing difficulty in going for walks.