2-year advanced melanoma survival benefit with dabrafenib, trametinib combination By Shreeya Nanda, Senior medwireNews Reporter Updated results from the COMBI-v trial display significantly improved overall and progression-free of charge survival with first-line dabrafenib as well as trametinib weighed against vemurafenib in patients with advanced melanoma. The results of the stage III trial comprising sufferers with BRAF V600E/K mutation-positive unresectable or metastatic melanoma were offered at the European Tumor Congress in Vienna, Austria, by Caroline Robert, from the Institut Gustave Roussy in Paris, France. A previous interim analysis with a median follow-up of 11 weeks showed a substantial improvement in OS with dabrafenib and trametinib, explained Robert in her presentation, so much so the trial was terminated early and sufferers in the vemurafenib group were allowed to crossover pharmacy .
This suggests better functionality of the 3D in dense breast tissue given 3D was wanted to patients regardless of breasts density or risk factors,’ Dr. Geisel said. Dr. Geisel observed that the majority of screening mammograms at her service now includes 3D imaging. ‘I am hopeful that my research will help raise consciousness among physicians and also women undergoing breast cancer screening,’ she said. Additional research must be done; ‘We acknowledge the numbers remain too small to attract significant conclusions, but the data is normally compelling,’ she said.. 3D plus 2D breasts imaging could be useful in detecting cancer in women with dense breasts 2D plus 3D breast imaging increases cancer detection rates by 11 percent, and may be useful in detecting malignancy in women with dense breasts particularly, a fresh study suggests.