There have been no significant distinctions between groups in virtually any other bronchoalveolar-lavage fluid or tissue cellular types examined . Epithelial Repair and Structural Remodeling Before the problems, there were no significant differences among the four groups regarding the histochemical measurements obtained .01) . Within the allergen and methacholine groupings, the increases after problem were significant , but there was no significant difference between the changes in these two groups . Epithelial Ki67 immunoexpression was increased after the challenges, with a significant difference between the challenge groupings and the control groups .This multi-year supply contract, having an initial term of five years, contains an annual use fee per each commercial end-item that includes our polymers. These hydrophilic polymers are being positioned for use across multiple products by this customer. By the end of the initial term, the agreement automatically renews for additional one year intervals if not previously terminated by either party. Khristine Carroll, AdvanSource’s Vice President of Sales and Marketing, stated, ‘The development agreement, entered into this past year with this leading multi-national medical device business, was a significant part of our vertical integration technique. We think that advancing this romantic relationship from product development to the supply of commercial polymers, designed to meet the specific requirements of our consumer specifically, validates our strategy to leverage our biomaterials technology and capabilities together with developers and manufacturers of medical devices.