Copyright 2009 Advisory Board Company and Kaiser Family Foundation. All rights reserved.. Achillion nominates ACH-2928 NS5A clinical candidate for treatment of HCV Achillion Pharmaceuticals, Inc. , a leader in the discovery and development of remedies for the most complicated infectious diseases, today announced the nomination of a lead clinical applicant in its 4th proprietary program against hepatitis C virus infection. The applicant, ACH-2928, can be an NS5A inhibitor that in preclinical studies has demonstrated superb potency against HCV RNA replication, along with very good safety and pharmacokinetic profiles. ‘The overall profile of ACH-2928 demonstrates that it is highly energetic and retains potency against HCV genotypes 1a and 1b, in addition to across additional genotypes.Back Pain Patients Seek TREATMENT First, Mobility Second: – MONDAY, Sept. 21, 2015 – – Treatment is a larger concern than flexibility for people with a common type of lower back pain referred to as lumbar spinal stenosis, a new study indicates. When asked to choose between a treatment that could reduce discomfort and one that would help them stand and walk, the vast majority of patients wanted to ease their discomfort, the researchers found.