Statistical Analysis We calculated a sample of 120 patients would provide 80 percent capacity to detect a hazard ratio of 0.54 for period to progression to symptomatic myeloma in the procedure group in comparison with the observation group. A one-sided test was used to estimate the sample size on the basis of the primary end stage because only the result in the expected path was to be examined. All efficacy analyses were predicated on the per-protocol human population, which was limited to the patients who fulfilled the eligibility requirements, but protection evaluations were predicated on the intention-to-treat populace. Results Patients and Treatment Between 8 November, 2007, june 9 and, 2010, a complete of 125 sufferers underwent randomization ; 57 individuals were designated to treatment with dexamethasone and lenalidomide, and 62 were assigned to observation .The problems associated with herbicide-resistant weeds are spreading and intensifying, especially weed species resistant to multiple products, like the mainstay of 21st hundred years agriculture, the herbicide glyphosate, said Bryan Youthful, Ph.D., a professor of Plant Soil and Agricultural Systems at Southern Illinois University in Carbondale who specializes in weed administration strategies. More than 200 specific weed species have already been verified resistant to at least a single herbicide, with infestations covering an incredible number of acres in the United States and 60 additional countries.